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WEBINARS

Discover upcoming and on-demand webinars covering best practices, emerging technologies, and expert insights in preclinical imaging and translational research. Learn from real-world applications across oncology, infectious disease, neuroscience, and more.

Upcoming Events

Considerations for Reducing & Refining Animal Research

Practical Advice for Adopting Human-Centric Models in Response to Recent Revisions to FDA & NIH Guidelines

Thursday, August 21, 2025
9 AM PDT  / 12 PM EDT / 6 PM CET

This webinar offers practical guidance on refining animal research and integrating human-centric models like organoids, computational simulations, and organ-on-a-chip systems. In light of recent FDA and NIH updates, researchers face new expectations around when and how to apply alternative methods responsibly and effectively.

Join us for a grounded discussion focused on model selection. We’ll explore where cellular models offer clear advantages, and where animal models remain essential for understanding disease complexity, drug response, and translational outcomes. You’ll leave with real-world examples, decision-making frameworks, and a clearer understanding of how to align your research with evolving standards without compromising scientific depth.

Previously Recorded Webinars:

Considerations for Reducing & Refining Animal Research

Practical Advice for Adopting Human-Centric Models in Response to Recent Revisions to FDA & NIH Guidelines

This webinar offers practical guidance on refining animal research and integrating human-centric models like organoids, computational simulations, and organ-on-a-chip systems. In light of recent FDA and NIH updates, researchers face new expectations around when and how to apply alternative methods responsibly and effectively.

Join us for a grounded discussion focused on model selection. We’ll explore where cellular models offer clear advantages, and where animal models remain essential for understanding disease complexity, drug response, and translational outcomes. You’ll leave with real-world examples, decision-making frameworks, and a clearer understanding of how to align your research with evolving standards without compromising scientific depth.

Growing a Small Animal Imaging Facility: Balancing Competing Demands

Elena Carlson, Preclinical Imaging Core Manager at Fred Hutchinson Cancer Center, gives an insightful presentation on managing a growing shared resource facility—covering everything from S10 grant management and scientific consulting, to marketing core services across a wider research institution.

Learn how to navigate the unique challenges posed for those working at the cross section of instrumentation and small animal work, and discover how custom workflows and strategic collaborations can support an expanding team.

Development of Image-Based In Vitro/In Vivo Platform for Targeting CAFs

Join Pengyu Huang, Ph.D. – Head of In Vivo Pharmacology at Simcere Zaiming & Simnova Biotherapeutics, in this webinar that explores cutting-edge methods to advance tumor microenvironment (TME) research, including:

  • Innovative Co-culture Systems: Learn how fluorescent protein-labeled cell lines (e.g., iRFP720, pKatushka) are used to create in vitro co-culture systems that replicate TME’s extracellular and cellular elements.
  • Translational Insights: Discover how in vitro experiments align with in vivo data, highlighting CAF-mediated tumor cell protection and the reshaping of cancer cell clusters to mimic human tumor tissue.
  • Key Findings: Gain insights into immune cell cytotoxicity kinetics and tumor resistance trends observed consistently across in vitro and in vivo studies.

Perfect for researchers looking to expand their knowledge of cancer biology and translational research.

Exosome-Mediated Delivery of Small Molecules, RNA & DNA for Development of Novel Cancer Therapeutics

Join Disha Moholkar, PhD for an introduction to how milk exosomes can be utilized for targeted drug delivery, & the latest advancements in RNA & DNA delivery using the Exosome-PEI-Matrix (EPM) technology.

Key topics include:

  • Exosomes as emerging nano-drug delivery vehicles
  • Bovine milk/colostrum derived exosome technology
  • Functionalized exosomes as vehicles for different cancer therapeutics: small molecules, RNA & DNA
  • Validation of in vivo anti-tumor efficacy of exosome technology using Spectral’s Ami HTX

Automatic, Real-time Acquisition of Bioluminescent Kinetic Curves

Join Dr. Andrew Van Praagh to learn how our new upcoming Aura software feature—Kinetics— ensures you are capturing peak data for optimal sensitivity and data reproducibility.

Key topics include:
– Why quantifying data captured at peak signal is critical to ensuring data accuracy and reproducibility
– An introduction to Kinetics, a new feature with the ability to automatically acquire bioluminescent kinetic curve data in real time, and how it enables the immediate identification of peak signal.
– A review of data from several animal oncology models including: The distinct types of bioluminescent kinetic curve profiles across various models and the occurrence of changing peak bioluminescent data onset times throughout a longitudinal study

Mastering Bioluminescent Imaging for Dynamic Biological Studies

Join Dr. Thomas Kirkland of Promega and Dr. Andrew Van Praagh of Spectral Instruments Imaging for an informative discussing the basic elements of in vivo BLI experimental design: the bioluminescent reporter protein, the reporter substrate, and the instrument you will use to measure the bioluminescent signal. Speakers also discuss key considerations for each of these elements and provide application examples, such as in vivo CAR-T cell tracking, that demonstrate how different experimental goals can influence your model design.

Optimizing Gene Expression with Bioluminescence & the piggyBac System

Discover how bioluminescence imaging and the piggyBac gene editing system optimize and track gene expression in mouse models. With Dr. Grace Walton of Hera Biolabs.

An In Vivo Perspective on Next Generation Heptamethine Cyanines for Optical Cancer Imaging

Join Subash Gamage of Notre Dame's Smith Lab for an in-depth presentation on the in vivo optical imaging applications of next-generation near-infrared heptamethine cyanine dye, including fluorescence-guided surgery & various cancer imaging applications.

Preclinical In Vivo Optical Imaging: A Research Service for Core & Animal Facilities

Join Michael Rule, MS for an introductory presentation on Preclinical In Vivo Optical Imaging as research service for core & animal facilities.

Originally recorded 4/25/2023 for The American Association for Laboratory Animal Science's (AALAS) annual Demo Day.

Anesthesia Considerations in Small Animal Imaging

Anesthetic gas is commonly used for the comfort and stability of animal models used in preclinical research. Join SII and Somni Scientific for an informative webinar discussing the proper use and removal of anesthetic gas to improve study accuracy and repeatability and minimize operator exposure.

Supporting Preclinical Drug Development with In Vivo Imaging

Advances in cancer therapeutics necessitate tumor models & treatment modalities that more closely replicate those seen in the clinic. Bioluminescent imaging (BLI) offers robust real-time visualization of tumor growth in mice and rats, including orthotopic, disseminated, & metastatic tumors. Data obtained from BLI may be used to assess tumor growth kinetics, metastatic deposits, & therapeutic efficacy. Join us to learn how Hera Biolabs uses in vivo imaging techniques that support pre-clinical drug development.

Quantitative Bioluminescent 3D Imaging

Validated in high impact publications such as Nature and Cell, InVivoPLOT represents the first automated, quantitative and non-destructive preclinical imaging method for 3D bioluminescence. Operated in the cloud and powered by artificial intelligence (AI), InVivoAX offers accurate automated image reconstruction, data processing and analysis anywhere.

Longitudinal, Non-invasive, Small Animal Imaging: How in vivo optical imaging can facilitate 3Rs compliant research

Join In Vivo Imaging Specialist, Michael Rule, for a brief introductory discussion on In vivo imaging modalities and their part in enabling the 3Rs.

Originally recorded for AALAS annual demo day

Molecular Imaging Study Design Basics

Join Dr. Mario Bourdon, CSO - BioLaurus Inc., for an informative webinar focused on key considerations for drug development studies. Topics include study outline, choosing a preclinical imaging modality, calculating sample size and more!

Application of New Bioluminescence Imaging Methods in Identification of Molecular Drivers of Cancer Pathogenesis

Join Dr. Mazur for an informative presentation focused on novel bioluminescence methods used in the identification of the NSD3 methyltransferase as a principal 8p11 amplicon-associated oncogenic driver in lung cancer.

The Roles of Preclinical Optical Imaging in Cancer Research

Join Dr. Michael Henry for an in depth presentation highlighting bioluminescence studies in oncology across a wide range of models. Discussion will also include site injection comparisons as well as generating and characterizing luciferase expressing cell lines. Dr. Henry also shares key data sets from his work spanning a 20 year career in molecular imaging.

Optical Imaging Webinar: Scientific Principles and Applications

Whole animal In vivo optical imaging: a high-sensitivity, high-throughput screening, and non-invasive imaging modality that can be applied to monitoring disease progression and its treatment in animal model systems. Join Lead Applications Scientist, Andrew Van Praagh, for an in-depth discussion of scientific principles and applications.

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