Tech Notes
Read scientific application notes and helpful tips
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How to Write a Winning Instrumentation GrantHow to Write a Winning Instrumentation Grant
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Optimizing Substrate Dosing for Reliable Bioluminescence Imaging (BLI)Optimizing Substrate Dosing for Reliable Bioluminescence Imaging (BLI)
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Extrapolating Tumor Volume from In Vivo Bioluminescence Signal ValuesExtrapolating Tumor Volume from In Vivo Bioluminescence Signal Values
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Why Transition from In Vitro to In Vivo Experiments?Why Transition from In Vitro to In Vivo Experiments?
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Troubleshooting Guide for BLI & FLI Optical Imaging: A Step-by-Step ApproachTroubleshooting Guide for BLI & FLI Optical Imaging: A Step-by-Step Approach
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Xenograft Tumor Model: Tips to Consider for ImagingXenograft Tumor Model: Tips to Consider for Imaging
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Key Considerations for Developing Animal Models for Optical ImagingKey Considerations for Developing Animal Models for Optical Imaging
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Guidelines for Establishing a Cancer Tumor Mouse Model for In Vivo Bioluminescence and Fluorescence ImagingGuidelines for Establishing a Cancer Tumor Mouse Model for In Vivo Bioluminescence and Fluorescence Imaging
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Enhancing Single-Cell Workflows with In Vivo Optical Imaging: A Focus on BLI & FLIEnhancing Single-Cell Workflows with In Vivo Optical Imaging: A Focus on BLI & FLI
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How In Vivo Optical Imaging Facilitates 3Rs Compliant ResearchHow In Vivo Optical Imaging Facilitates 3Rs Compliant Research
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Understanding Absolute CalibrationUnderstanding Absolute Calibration
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Rodent Depilation for Optical ImagingRodent Depilation for Optical Imaging
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How to Open Living Image Files in AuraHow to Open Living Image Files in Aura
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How to Quantify Bioluminescent CellsHow to Quantify Bioluminescent Cells
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10 Tips and Tricks for In Vivo Imaging10 Tips and Tricks for In Vivo Imaging
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Science of Optical Imaging: How it worksScience of Optical Imaging: How it works
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Reporter Expression: Helpful Tips on Model DevelopmentReporter Expression: Helpful Tips on Model Development
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Comparing In Vivo Optical Imaging to Other Modalities (MRI/CT/PET/SPECT/US)Comparing In Vivo Optical Imaging to Other Modalities (MRI/CT/PET/SPECT/US)
Literature
View our product brochures and case studies
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8 Reasons to Choose Spectral8 Reasons to Choose Spectral
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Lago BrochureLago Brochure
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Ami BrochureAmi Brochure
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Kino BrochureKino Brochure
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Aura BrochureAura Brochure
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Lago X-Cube Optical CTLago X-Cube Optical CT
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Quantitative 3D Optical ImagingQuantitative 3D Optical Imaging
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DecaFlow Animal Management SystemDecaFlow Animal Management System
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PentaFlow Animal Management SystemPentaFlow Animal Management System
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City of Hope Case StudyCity of Hope Case Study
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Considerations for Reducing & Refining Animal Research and Adopting Human-Centric ModelsConsiderations for Reducing & Refining Animal Research and Adopting Human-Centric Models
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Growing a Small Animal Imaging Facility: Balancing Competing DemandsGrowing a Small Animal Imaging Facility: Balancing Competing Demands
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Development of Image-Based In Vitro/In Vivo Platform for Targeting CAFsDevelopment of Image-Based In Vitro/In Vivo Platform for Targeting CAFs
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Exosome-Mediated Delivery of Small Molecules, RNA & DNA for Development of Novel Cancer TherapeuticsExosome-Mediated Delivery of Small Molecules, RNA & DNA for Development of Novel Cancer Therapeutics
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Automatic, Real-time Acquisition of Bioluminescent Kinetic CurvesAutomatic, Real-time Acquisition of Bioluminescent Kinetic Curves
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Mastering Bioluminescent Imaging for Dynamic Biological StudiesMastering Bioluminescent Imaging for Dynamic Biological Studies
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Optimizing Gene Expression with Bioluminescence & the piggyBac SystemOptimizing Gene Expression with Bioluminescence & the piggyBac System
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An In Vivo Perspective on Next Generation Heptamethine Cyanines for Optical Cancer ImagingAn In Vivo Perspective on Next Generation Heptamethine Cyanines for Optical Cancer Imaging
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Preclinical In Vivo Optical Imaging: A Research Service for Core & Animal FacilitiesPreclinical In Vivo Optical Imaging: A Research Service for Core & Animal Facilities
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Anesthesia Considerations in Small Animal ImagingAnesthesia Considerations in Small Animal Imaging
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Supporting Preclinical Drug Development with In Vivo ImagingSupporting Preclinical Drug Development with In Vivo Imaging
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Quantitative Bioluminescent 3D ImagingQuantitative Bioluminescent 3D Imaging
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Molecular Imaging Study Design BasicsMolecular Imaging Study Design Basics
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Application of New Bioluminescence Imaging Methods in Identification of Molecular Drivers of Cancer PathogenesisApplication of New Bioluminescence Imaging Methods in Identification of Molecular Drivers of Cancer Pathogenesis
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Longitudinal, Non-invasive, Small Animal Imaging: How in vivo optical imaging can facilitate 3Rs compliant researchLongitudinal, Non-invasive, Small Animal Imaging: How in vivo optical imaging can facilitate 3Rs compliant research
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The Roles of Preclinical Optical Imaging in Cancer ResearchThe Roles of Preclinical Optical Imaging in Cancer Research
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Optical Imaging Webinar: Scientific Principals and ApplicationsOptical Imaging Webinar: Scientific Principals and Applications
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How to Adjust the Color Range Bar - Aura 4.0 TutorialHow to Adjust the Color Range Bar - Aura 4.0 Tutorial
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Toolbox Overview - Aura 4.0 TutorialToolbox Overview - Aura 4.0 Tutorial
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How to analyze data from Living Image® with free Aura analysis softwareHow to analyze data from Living Image® with free Aura analysis software
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How to Acquire Data Using Easy Mode - Aura 4.0 TutorialHow to Acquire Data Using Easy Mode - Aura 4.0 Tutorial
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Highlighted New Features - Aura 4.0 TutorialHighlighted New Features - Aura 4.0 Tutorial
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How to Acquire Data Using the Group Acquire Feature - Aura 4.0 TutorialHow to Acquire Data Using the Group Acquire Feature - Aura 4.0 Tutorial
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How to Acquire BLI Data Using Luminescence Classic Mode - Aura 4.0 TutorialHow to Acquire BLI Data Using Luminescence Classic Mode - Aura 4.0 Tutorial
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How to Acquire FLI Data Using Fluorescence Classic Mode - Aura 4.0 TutorialHow to Acquire FLI Data Using Fluorescence Classic Mode - Aura 4.0 Tutorial
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How to Acquire X-ray Data - Aura 4.0 TutorialHow to Acquire X-ray Data - Aura 4.0 Tutorial
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How to Perform ROI Analysis - Aura 4.0 TutorialHow to Perform ROI Analysis - Aura 4.0 Tutorial
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How to Reveal Hidden Signals by Adjusting Dynamic Range - Aura 4.0 TutorialHow to Reveal Hidden Signals by Adjusting Dynamic Range - Aura 4.0 Tutorial
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How to Save Images for Presentation - Aura 4.0 TutorialHow to Save Images for Presentation - Aura 4.0 Tutorial
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How to Save & Restore ROIs - Aura 4.0 TutorialHow to Save & Restore ROIs - Aura 4.0 Tutorial
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How to use the Save Experiment Feature - Aura 4.0 TutorialHow to use the Save Experiment Feature - Aura 4.0 Tutorial
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Aura Imaging Software v 4.0: Complete Analysis TutorialAura Imaging Software v 4.0: Complete Analysis Tutorial
Review our curated publications list. Browse by Field of Study, Modality, Probe & Cell line.
Posters
View recent posters presented by Spectral Instruments Imaging scientists & engineers
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A Multimodal Animal Cradle Inlay System to Facilitate Optical, PET, MCT, & MRI Co-Registrations of a Metastatic, Colorectal Cancer Syngeneic Mouse ModelA Multimodal Animal Cradle Inlay System to Facilitate Optical, PET, MCT, & MRI Co-Registrations of a Metastatic, Colorectal Cancer Syngeneic Mouse Model
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Multimodality in Longitudinal Lung Metastasis Study: Achieving Optimal Sensitivity & Functional EvaluationMultimodality in Longitudinal Lung Metastasis Study: Achieving Optimal Sensitivity & Functional Evaluation
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Automated, Real-Time Acquisition & Quantification of Peak, Plateau-Phase In Vivo Bioluminescent DataAutomated, Real-Time Acquisition & Quantification of Peak, Plateau-Phase In Vivo Bioluminescent Data
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Kinetics Automated Software Technology Dramatically Improves how In Vivo BL Data is Acquired & QuantifiedKinetics Automated Software Technology Dramatically Improves how In Vivo BL Data is Acquired & Quantified
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Automated, Fast, High-Sensitivity Optical Imaging with the Spectral Instruments Imaging Lago XAutomated, Fast, High-Sensitivity Optical Imaging with the Spectral Instruments Imaging Lago X
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Comparison of High Sensitivity BLI Imaging Systems for Ultra-weak Signal ApplicationsComparison of High Sensitivity BLI Imaging Systems for Ultra-weak Signal Applications
Quick Tips for In Vivo Imaging Success
Watch short helpful videos, ask a question, or share a quick tip of your own!
Get Your Questions Answered
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10 Considerations for Animal Model Development with Preclinical In Vivo Optical Imaging10 Considerations for Animal Model Development with Preclinical In Vivo Optical Imaging
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What is Absolute Calibration?What is Absolute Calibration?
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How to analyze data from Living Image® with free Aura analysis softwareHow to analyze data from Living Image® with free Aura analysis software
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What Units Should You Use to Quantify Bioluminescent Signal?What Units Should You Use to Quantify Bioluminescent Signal?
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How to Detect Both Strong and Weak Signals with Preclinical Optical ImagingHow to Detect Both Strong and Weak Signals with Preclinical Optical Imaging
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To Shave Or Not to Shave? Hair removal considerations when performing small animal imagingTo Shave Or Not to Shave? Hair removal considerations when performing small animal imaging
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Check out our new Quick Tips for in vivo imaging success!Check out our new Quick Tips for in vivo imaging success!
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How to Select the Correct Excite and Emission Filter Pairs for Fluorescent ImagingHow to Select the Correct Excite and Emission Filter Pairs for Fluorescent Imaging
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Why Use Efficiency Units for FLI AnalysisWhy Use Efficiency Units for FLI Analysis
